Selected Publications (2000 to date):From my Doctoral Research Studies | From my Post-doctoral research studies | From my Group
FROM MY DOCTORAL RESEARCH STUDIESFrom my Ph.D. thesis in the Dujardin group at Centre de Génétique Moléculaire, Gif-sur-Yvette, France
(1) Bonnefoy, N., Chalvet, F., Hamel, P., Slonimski, P.P. & Dujardin G., (1994) OXA1, a Saccharomyces cerevisiae nuclear gene whose sequence is conserved from prokaryotes to eukaryotes controls cytochrome oxidase biogenesis. J. Mol. Biol., 239, 201-212. [pdf]
(2) Hamel, P., Sakamoto, W., Wintz, H. & Dujardin, G., (1997) Functional complementation of an oxa1- yeast mutation identifies an Arabidopsis thaliana cDNA involved in the assembly of respiratory complexes. Plant J., 12, 1319-1327. [pdf]
(3) Hamel, P., Lemaire, C., Bonnefoy, N., Brivet-Chevillotte, P. & Dujardin G., (1998) Mutations in the membrane anchor of yeast cytochrome c1 compensate for the absence of Oxa1p and generate carbonate-extractable forms of cytochrome c1. Genetics, 150, 601-611. [pdf](4) Cardazzo, B., Hamel, P., Wintz, H., Sakamoto, W. & Dujardin, G., (1998). Isolation of an Arabidopsis thaliana cDNA by complementation of a yeast abc1 deletion mutant deficient in complex III respiratory activity. Gene, 221, 117-125. [pdf]
(5) Lemaire, C., Hamel, P., Velours, J. and Dujardin, G. (2000) Absence of the mitochondrial AAA protease Yme1p restores ATPase F0 subunit accumulation in an oxa1 deletion mutant of Saccharomyces cerevisiae. J. Biol. Chem. 275, 23471-23475. [pdf]
(6) Saint-Georges, Y., Hamel, P., Lemaire, C., and Dujardin, G. (2001) Role of positively-charged transmembrane segments in the insertion and assembly of mitochondrial inner-membrane proteins. PNAS, 98, 13814-13819. [pdf]
(7) Hamel, P., Saint-Georges, Y., Altamura N., de Pinto, B. and Dujardin, G. (2004) Redundancy in the function of mitochondrial phosphate transport in Saccharomyces cerevisiae and Arabidopsis thaliana. Mol. Microbiol. 51, 307-317. [pdf]
From my japanese experience at BERI and University of Tokyo in Japan
(8) Arai, M., Hamel, P., Kanaya, E., Inaka, K., Miki, K., Kikuchi, M. & Kuwajima, K. (2000) Effect of an alternative disulfide bond on the structure, stability and folding of human lysozyme. Biochemistry. 39, 3472-3479. [pdf]
FROM MY POST-DOCTORAL RESEARCH STUDIES
From my post-doctoral studies in the Wollman group at IBPC in Paris, France
(9) Hamel, P., Olive, J., Pierre, Y., Wollman, F.-A. & de Vitry, C. (2000) A new subunit of cytochrome b6 f complex undergoes reversible phosphorylation upon state transition. J. Biol. Chem. 275, 17072-17079. [pdf]
From my post-doctoral studies in the Merchant group at UCLA
(10) Nakamoto, S., Hamel, P. & Merchant, S., (2000) Assembly of chloroplast cytochromes b and c. Biochimie. 82, 603-614. [pdf]
(11) Hamel, P., Dreyfuss, B., Xie, Z., Gabilly, S. and Merchant S. (2003) Essential histidine and tryptophan residues in CcsA, a system II polytopic cytochrome c biogenesis protein. J. Biol. Chem. 278, 2593-2603. [pdf]
(12) Dreyfuss, B., Hamel, P., Nakamoto, S. and Merchant S. (2003) Functional analysis of a divergent system II protein, Ccs1, involved in c-type cytochrome biogenesis. J. Biol. Chem. 278, 2604-2613. [pdf]
(13) Page, M*.,Hamel, P*., Gabilly, S., Zegzouti, H, Perea, J., Alonso, J., Ecker, J., Theg, S., Christensen, S., and Merchant, S. (2004) A homolog of the prokaryotic thiol-disulfide transporter CcdA is required for the assembly of the cytochrome b6f complex in Arabidopsis chloroplasts. J. Biol. Chem. 279, 32474-32482. [pdf]
(* equal contribution)(14) Bernard, D., Gabilly, S., Dujardin, G., Merchant, S. and Hamel, P. (2003) Overlapping specificities of the cytochrome c and c1 heme lyases. J. Biol. Chem. 50, 49732-49742. [pdf]
(15) Bernard, D., Quevillon-Cheruel S., Merchant, S., Guiard, B. and Hamel, P. (2005) Cyc2p, a membrane-bound flavoprotein involved in the maturation of mitochondrial c-type cytochromes. J. Biol. Chem. 280, 39852-398549. [pdf]
(16) Remacle, C., Barbieri, M.R., Cardol, P., Hamel. P. (2008) Eukaryotic complex I: functional diversity and experimental systems to unravel the assembly process. Mol Genet Genomics (2008) 280:93–110
(17) Hanikenne M., Merchant, S. and Hamel, P. (2008) Transition metal nutrition: a balance between deficiency and toxicity in The Chlamydomonas Sourcebook:Organellar and Metabolic Processes (Ed. D. Stern, Publisher: Elsevier Inc.). Volume 2:333-400.
(18) Hamel, P., Corvest, V., Giegé, P., Bonnard, G. (2009) Biochemical requirements for the maturation of mitochondrial c-type cytochromes. Biochimica et Biophysica Acta 1793 (2009) 125–13.