Selected Publications (2000 to date):From my Doctoral Research Studies | From my Post-doctoral research studies | From my Group
FROM MY DOCTORAL RESEARCH STUDIESFrom my Ph.D. thesis in the Dujardin group at Centre de Génétique Moléculaire, Gif-sur-Yvette, France
(1) Bonnefoy, N., Chalvet, F., Hamel, P., Slonimski, P.P. & Dujardin G., (1994) OXA1, a Saccharomyces cerevisiae nuclear gene whose sequence is conserved from prokaryotes to eukaryotes controls cytochrome oxidase biogenesis. J. Mol. Biol., 239, 201-212. [pdf]
(2) Hamel, P., Sakamoto, W., Wintz, H. & Dujardin, G., (1997) Functional complementation of an oxa1- yeast mutation identifies an Arabidopsis thaliana cDNA involved in the assembly of respiratory complexes. Plant J., 12, 1319-1327. [pdf]
(3) Hamel, P., Lemaire, C., Bonnefoy, N., Brivet-Chevillotte, P. & Dujardin G., (1998) Mutations in the membrane anchor of yeast cytochrome c1 compensate for the absence of Oxa1p and generate carbonate-extractable forms of cytochrome c1. Genetics, 150, 601-611. [pdf](4) Cardazzo, B., Hamel, P., Wintz, H., Sakamoto, W. & Dujardin, G., (1998). Isolation of an Arabidopsis thaliana cDNA by complementation of a yeast abc1 deletion mutant deficient in complex III respiratory activity. Gene, 221, 117-125. [pdf]
(5) Lemaire, C., Hamel, P., Velours, J. and Dujardin, G. (2000) Absence of the mitochondrial AAA protease Yme1p restores ATPase F0 subunit accumulation in an oxa1 deletion mutant of Saccharomyces cerevisiae. J. Biol. Chem. 275, 23471-23475. [pdf]
(6) Saint-Georges, Y., Hamel, P., Lemaire, C., and Dujardin, G. (2001) Role of positively-charged transmembrane segments in the insertion and assembly of mitochondrial inner-membrane proteins. PNAS, 98, 13814-13819. [pdf]
(7) Hamel, P., Saint-Georges, Y., Altamura N., de Pinto, B. and Dujardin, G. (2004) Redundancy in the function of mitochondrial phosphate transport in Saccharomyces cerevisiae and Arabidopsis thaliana. Mol. Microbiol. 51, 307-317. [pdf]
From my japanese experience at BERI and University of Tokyo in Japan
(8) Arai, M., Hamel, P., Kanaya, E., Inaka, K., Miki, K., Kikuchi, M. & Kuwajima, K. (2000) Effect of an alternative disulfide bond on the structure, stability and folding of human lysozyme. Biochemistry. 39, 3472-3479. [pdf]
FROM MY POST-DOCTORAL RESEARCH STUDIES
From my post-doctoral studies in the Wollman group at IBPC in Paris, France
(9) Hamel, P., Olive, J., Pierre, Y., Wollman, F.-A. & de Vitry, C. (2000) A new subunit of cytochrome b6 f complex undergoes reversible phosphorylation upon state transition. J. Biol. Chem. 275, 17072-17079. [pdf]
From my post-doctoral studies in the Merchant group at UCLA
(10) Nakamoto, S., Hamel, P. & Merchant, S., (2000) Assembly of chloroplast cytochromes b and c. Biochimie. 82, 603-614. [pdf]
(11) Hamel, P., Dreyfuss, B., Xie, Z., Gabilly, S. and Merchant S. (2003) Essential histidine and tryptophan residues in CcsA, a system II polytopic cytochrome c biogenesis protein. J. Biol. Chem. 278, 2593-2603. [pdf]
(12) Dreyfuss, B., Hamel, P., Nakamoto, S. and Merchant S. (2003) Functional analysis of a divergent system II protein, Ccs1, involved in c-type cytochrome biogenesis. J. Biol. Chem. 278, 2604-2613. [pdf]
(13) Page, M*.,Hamel, P*., Gabilly, S., Zegzouti, H, Perea, J., Alonso, J., Ecker, J., Theg, S., Christensen, S., and Merchant, S. (2004) A homolog of the prokaryotic thiol-disulfide transporter CcdA is required for the assembly of the cytochrome b6f complex in Arabidopsis chloroplasts. J. Biol. Chem. 279, 32474-32482. [pdf]
(* equal contribution)(14) M. Dudley Page, Janette Kropat, Hamel, P, and Sabeeha S. Merchant (2009) Two Chlamydomonas CTR Copper Transporters with a Novel Cys-Met Motif Are Localized to the Plasma Membrane and Function in Copper Assimilation. The Plant Cell. In Print. [pdf]
(15) Bernard, D., Gabilly, S., Dujardin, G., Merchant, S. and Hamel, P. (2003) Overlapping specificities of the cytochrome c and c1 heme lyases. J. Biol. Chem. 50, 49732-49742. [pdf]
(16) Bernard, D., Quevillon-Cheruel S., Merchant, S., Guiard, B. and Hamel, P. (2005) Cyc2p, a membrane-bound flavoprotein involved in the maturation of mitochondrial c-type cytochromes. J. Biol. Chem. 280, 39852-398549. [pdf]
(17) Remacle, C., Barbieri, M.R., Cardol, P., Hamel. P. (2008) Eukaryotic complex I: functional diversity and experimental systems to unravel the assembly process. Mol Genet Genomics (2008) 280:93–110
(18) Hanikenne M., Merchant, S. and Hamel, P. (2008) Transition metal nutrition: a balance between deficiency and toxicity in The Chlamydomonas Sourcebook:Organellar and Metabolic Processes (Ed. D. Stern, Publisher: Elsevier Inc.). Volume 2:333-400.
(19) Hamel, P., Corvest, V., Giegé, P., Bonnard, G. (2009) Biochemical requirements for the maturation of mitochondrial c-type cytochromes. Biochimica et Biophysica Acta 1793 (2009) 125–13.
(20) Claire Remacle, Sara Cline, Layla Boutaffala, Stephane Gabilly, Veronique Larosa, M. Rosario Barbieri, Nadine Coosemans, and Hamel, P. (2009) The ARG9 Gene Encodes the Plastid-Resident N-Acetyl Ornithine Aminotransferase in the Green Alga Chlamydomonas reinhardtii. EUKARYOTIC CELL, Sept. 2009, p. 1460–1463. [pdf]