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Graduate Directory

 

Chemistry Department Graduates

College of Math & Physical Sciences: AS OF june 2008

 

  • Adefarati, Akin - M.S., WI88 Advisor: Dr. Heinz Floss Thesis Title: Isolation, structure elucidation and biosynthesis of a new polyketide-derived metaolite of Streptomyces coelicolor mutant B40.

  • Beebe, Kirk - Ph.D., AU2000 Advisor:  Dr. Dehua Pei Dissertation Title:  Substrate recognition through modular domains:  protein tyrosine phosphatase SHP-1 and tail-specific protease (TSP). Employment: Post -Doctoral Fellow at Scripps Research Institute

  • Biswas, Roopa - Ph.D., SP97 Advisor:  Dr. Muttaiya Sundaralingam Dissertation/Thesis Title: Crystal Structures of Alternating RNA Oligomers: Tandem G-U Wobble Pairs. Employment: Post-Doc in the lab of Dr. Venkat Gopalan, Dept. of Biochemistry, Ohio State University Current Position:  Assistant Professor, Uniformed Services University of the Health Sciences, Graduate School of Nursing

  • Bullinger, Patrick - M.S., SU98 Advisor:  Dr. Ross Dalbey Dissertation/Thesis Title: Purification and Activity Studies on a Soluble Fragment of Type I Signal Peptidase from Bacillus subtilis. Employment: Scientific Information Analyst, Chemical Abstracts, Columbus, Ohio

  • Cao, Guoqing - Ph.D., WI95 Advisor:   Dr. Ross Dalbey Dissertation/Thesis Title: Studies on the membrane protein assembly in Eschericha Coli: N-terminal tail translocation and the role of the electrochemical potential in membrane insertion. Employment: Postdoctoral Fellowship, Univ. of Texas Southwestern Medical Center

  • Carlos, Joseph - Ph.D., AU2000 Advisor:  Dr. Ross Dalbey Dissertation Title:  Type I Signal Peptidases of E. coli, B. subtilis, and S. pneumoniae:  Mechanistic Analysis, Isolation, and Characterization. Employment: Employed as Research Scientist by Ross Labs, Columbus, Ohio

  • Minyong Chen - Ph.D., AU 2002 Advisor:  Dr. Ross Dalbey Dissertation Title:  Employment: Post-Doctoral Fellow, Chemistry Dept., The Ohio State University

  • Cheng, Shiyuan - Ph.D., SU92 Advisor:  Dr. Ross Dalbey Dissertation Title: Membrane assembly studies of subunit h: leader peptidase and m13 procoat proteins in Escherichia Coli.

  • DeFelippis, Michael - Ph.D., SP90 Advisor:  Dr. Michael Klapper Dissertation Title: The Redox Potentials of the Tyrosine and Tryptophan Radicals and Long-range Electron Transfer Between Tyrosine and Tryptophan in Peptides.

  • Hamilton, Kelly - M.S., SU91 Advisor:  Dr. Ming-Daw Tsai Thesis Title: Structure-function studies on surface lysines of bovine pancreatic phospholipase A2. Current Position:  Research Assistant, Johns Hopkins Allergy and Asthma Center (with Dr. Farhad Imani)

  • Heiny, Layne - M.S., WI87 (Dr. Marita King, Advisor) Thesis Title: Chemical modification of the Ca2+- and calmodulin-regulated phosphatase, calcineurin.

  • Herrold, Richard - M.S., SU86 Advisor:  Dr. Heinz Floss Thesis Title: Studies on the biosynthesis of asukamycin and acarbose.

  • Hu, Xintong - M.S., SU93 Adviosor:  Dr. Ross Dalbey Thesis Title: Positively charged residues influence the PF3 coat protein insertion and topology.

  • Huang, Baohua - Ph.D., SU95 Advisor:  (Dr. Ming-Daw Tsai Dissertation Title: Protein Engineering: From Structure-Function Relation Studies of Phospholipase A2 to Rational Design of a Novel Restriction Endonuclease Current Position:  Post-Doctoral Fellow, Abbott Laboratories

  • Husman, David - Ph.D., SU88 Advisor:  Dr. Robert Mayer Dissertation Title: Removal of detergents from dextrasucrase and the effects they have on enzyme activity and structure.

  • Jin, Yan - Ph.D., SU 06 Advisor: Dr. James Cowan Dissertation: In Vitro and In Vivo Studies of DNA Cleavage and Targteted Cleavage of HIV Rev Response Element RNA by Metallopeptides Employment: Post-Doctoral Fellow, Ohio State University

  • Jou, Ruwen - Ph.D., AU91 Advisor:  Dr. James Cowan Dissertation Title: Metallobiochemistry of ribonuclease H and mannuron C-5 epimerase.

  • Kwak, Jae-Gyu - M.S., WI91 Advisor:  Dr. Ming-Daw Tsai Thesis Title: Studies on the Function of Aspartate 99 and Lysine 56 of Bovine Pancreatic Phospholipase A2 Current Position:  American Cyanamide

  • Kwiatkowski, Anne - Ph.D., AU88 Advisor:  Dr. Marita King Dissertation Title: Structure, function and regulation of type II calmodulin-dependant protein kinase.

  • Laws, Joan - M.S., AU89 Advisor:  Dr. Ross Dalbey Thesis Title: Polar residues can play a role in membrane translocation.

  • Lee, Jong-In - Ph.D., SU91 Advisor:  Dr. Ross Dalbey Dissertation Title: Membrane assembly and function of Escherichia coli leader peptidase.

  • Li, Yishan - Ph.D., SU94 Advisor:  Dr. Ming-Daw Tsai Dissertation Title: Structure-function studies of phospholipase A2: a site-directed mutagenesis and nuclear magnetic resonance study. Current Position:  Group Leader, Peptide-Antibody Development, Santa Cruz Biotechnology, Santa Cruz, CA

  • Liao, Hua - Ph.D., AU99 Advisor:  Dr. Ming-Daw Tsai Dissertation Title:  Structure and Function of FHA2 Domain of RAD53, a New Phosphopeptide Binding Domain and Mechanistic Studies of   Phosphatidylinositio-Specific Phospholipase" Employment:Postdoc, Harvard Institute of Proteomics at Harvard Medical School Current Position:  Millenium Pharmaceuticals

  • Liu, Xiaohong - Ph.D., SU96 Advisor:  Dr. Ming-Daw Tsai Dissertation Title: Structure-function relationship studies of bovine pancreatic phospholipase A2 and chicken muscle adenylate kinase. Current Position:  Postdoctoral Fellow at Harvard Medical School

  • Liu, Yushi - Ph.D., SP 07 Advisor: Dr. James Cowan, Chemsitry Department Dissertation Title: Characterization of the Human NFU and its Interaction with the Molecular Chaperone System" Position:

  • Makroglou, George - M.S., AU87 Advisor:  Dr. Heinz Floss Dissertation Title: Studies in the steric course of the methylation of DNA and model compounds by N-methyl-N-nitrosourea and N, N-dimethylnitrosamine carrying chiral methyl groups.

  • Mamone, Anthony - M.S., AU90 Advisor:  Dr. Ming-Daw Tsai Thesis Title: Testing the function of the conserved residue phenylalanine106 of bovine pancreatic phospholipase A2. Current Position: U.S. Biochemicals, Cleveland, Ohio

  • Mansy, Sheref - Ph.D., SU 03 Advisor:  Dr. James Cowan Dissertation Title:  Structure and Function of Iron-Sulfur Cluster Biosynthesis Proteins and the Influence of Oxygen Ligation Position after graduation:  Post-Doctoral Associate, Mass. General Hospital, Harvard University 

  • Melillo, Allegra - M.S., SP98 Advisor:  Dr. Ming-Daw Tsai Thesis Title: Protein Engineering: Using Site-Directed Mutagenesis To Improve The Catalytic Efficiency Of A Novel Restriction Endonuclease: Splase. Employment: Enrolled in Medical School, Baylor University

  • Nuth, Manunya - Ph.D. SU04 Advisor:  Dr. James Cowan Employment: Post-Doctoral Researcher, University of Pennsylvania, School of Biomedical Engineering

  • Paul O'Maille - Ph.D. Au 2001 Advisor:  Dr. Ming-Daw Tsai Dissertation Title:  Combinatorial protein engineering by structure-based gene shuffling Employment: Post-Doctoral Fellow, Chemistry Department, Ohio State University:

  • Oths, Phil - M.S., WI88 Advisor:  Dr. Heniz Floss Thesis Title: Investigation into the stereochemical course of the reaction catalyzed by GDP-mannose oxidoreductase.

  • Plank-Herrick, Minnie - M.S., SU93 Advisor:  Dr. Marita King Dissertation/Thesis Title: Chemical modification of calcineurin and the production of its recombinant catalytic subunit. Employment: High School Teacher

  • Poi, Ming Jye - Ph.D., AU 2001 Advisor:  Dr. Ming-Daw Tsai Dissertation Title:  Low barrier hydrogen bonding in bovine pancreatic phospholipase A2 and somatic INK4A-ARF locus mutations:  a significant mechanism of gene inactivation in head and neck squamous cell carcinomas. Employment: Attending Ohio State University for Pharmacy Degree

  • Politino, Michael - Ph.D., SU89 Advisor:  Dr. Marita King Dissertation Title: Calcium- and calmodulin-sensitive interactions of calcineurin with phospholipids.

  • Qin, Dongyan  - Ph.D., SU 03 Advisor:  Dr. Ming-Daw Tsai Dissertation Title:  Specificity and Structural Moedling of FHA domain of CHK2 and a General Characterization of FHA Domain of Caenor Habditis Elegans Current Position:  Postodoctoral Fellow, Dept. of Chemistry, The Ohio State University

  • Riddle, Suzette - Ph.D., WI97 Advisor:  Dr. Ming-Daw Tsai Dissertation Title: Purification and characterization of 2 recombinant proteins: annexin 3 and phosphatidyl inositol specific phospholipase. Current Position:  Postdoctoral Fellow/Research Associate at National Jewish Institute for Respiratory and Immunological Research (W. Dr. Carl White, M.D.)

  • Samuelson, James - Ph.D., AU2000 Advisor:  Dr. Ross Dalbey Dissertation Title: The Essential Role of YidC in Bacterial Protein Insertion Employment: Post-Doctoral Fellow, New England Biolabs, Beverly, MD

  • Sarvis, Harry - Ph.D., SP90 Advisor:  Dr. Ming-Daw Tsai Dissertation Title: Physical studies of thiophospholipids using Fourier transform infrared spectroscopy. Employment: Director, Ohio Environmental Protection Agency

  • Schaeffer, Chris - Ph.D., SP98 Advisor:  Dr. Ming-Daw Tsai Dissertation Title: Characterization of New Restriction Endonuclease: Splase. Employment: Medical student, University of Cincinnati Current Position:  Resident - Radiology, Cleveland Clinic

  • Sen, Sabrina - M.S. - SP 07 Advisor: Dr. Ross Dalbey

  • Shin, Jinu - M.S., SU99 Advisor:  Dr. Dehua Pei Thesis Title:  Substrate Recognition Through a PDZ Domain in Tail Specific Protease

  • Song, Haiyan - Ph.D., WI08 Advisor: Dr. Ming-Daw Tsai Dissertation: Structural and Functional Study of the Interaction Between KI67 FHA Domain and NIFK

  • Suzuki, Erika - Ph.D., SU93 Advisor:  Dr. Marita King Dissertation/Thesis Title: Structure, function, and regulation of type 2 calmodulin-dependent protein kinase

  • Sweeney, Michael - Ph.D. SU 05 Advisor: Dr. Dehua Pei Dissertation: Synthetic Combinatorial Peptiode Libraries and Their Application in Decoding Biological Interactions Employment: Attending Medical School

  • Thompson, Mark - Ph.D., WI91 Advisor:  Dr. Heinz Floss Dissertation Title: Studies on the formation of 3,6- and 2,6-dideoxyhexoses.

  • Tian, Gaochao - Ph.D., AU88 Advisor:  Dr. Ming-Daw Tsai Dissertation Title: Mutagenic, stereochemical, and kinetic analyses of the structure and function of adenylate kinase.

  • Tippin, Douglas - M.D./Ph.D., SU95 Advisor:  Dr. Muttaiya Sundaralingam Dissertation/Thesis Title: Crystallographic investigation of A-DNA conformations: the effect of hydration, methylation and spermine binding. Employment: Partner, Littleton Radiation Oncology, Littleton, CO

  • Wei, Yaoming - Ph.D., SU99 Advisor:  Dr. Dehua Pei Dissertation/Thesis Title:  Peptide Deformylase:  Characterization and Antibacterial Drug Design Employment: Post-doc w. Dr. Perry Frey, Institute for Enzyme Research,Madison, Wisconsin

  • Woodman, Robert - Ph.D., SP91 Advisor:  Dr. Heinz Floss Dissertation/Thesis Title: Molecular and biochemical studies on thiopeptide antibiotic biosynthesis.

  • Wu, Jiejun - Ph.D., SU89 Advisor:  Dr. Alan Marshall Dissertation/Thesis Title: Investigation of wheat germ 5S ribosomal RNA common arm fragment solution structures by high resolution nuclear magnetic resonance.

  • Xu, Rong - M.S., AU 02 Advisor: Dr. Ross Dalbey Thesis: The Interaction of Escherichia Coli ATPase Subunit A with YidC During Membrane Insertion

  • Yan, Honggao - Ph.D., SP91 AdvisorL  Dr. Ming-Daw Tsai Dissertation/Thesis Title: Mechanism of adenylate kinase: a site-directed mutagenesis and nuclear magnetic resonance study. Employment: Assistant Professor, Dept of Biochemistry, Michigan State University, East Lansing, MI.

  • Yongkiettrakul, Suganya - Ph.D., SP 04 Advisor:  Dr. Ming Daw Tsai Dissertation Title:  Molecular Structure and Specific Interaction of FHA Domains of Saccharomyces Cerevisiae RAD53 Employment: Research Scientist, The National Science and Technology Development Agency, Biotech Division, Thailand

  • Yuan, Jijun - Ph.D., WI 08 Advisor: Dr. Ross Dalbey Dissertation: Membrane Protein Insertaion in Bacteria by the YidC and Sec Pathway Employment: Post-Doctoral Researcher, Dept. of Chemistry, Ohio State University

  • Zhang, Xiaoyan - M.S., WI94 Advisor:  Dr. Ming-Daw Tsai Thesis Title: Design, synthesis and biological activities of 4-substituted imidazoles as (alpha) 2-adrenoceptor agonists. Employment:  Bristol-Myers, Wallingford, CT

  • Zhou, Bin-bin - M.S., SU89 Advisor:  Dr. Ming-Daw Tsai Thesis Title: The study of adenylate kinase substrate binding sites by site-directed mutagenesis. Employment:  Postdoc, Harvard Medical School

  • Zhu, Hongxin - Ph.D., AU95 Advisor:  Dr. Ming-Daw Tsai Dissertation Title: Structure-function studies of bovine pancreatic phospholipase A2: the roles of N-terminal residues in the interfacial activation and the roles of disulfide bonds in the structure, stability, and catalytic function cloning, expression, purification, and functional studies of a potential human HIV-1 repressor gene. Employment: Postdoc, Boston University (lab of Charles Cantor)

  • Zhu, Jinge Grace - Ph.D., SP 05 Advisor: Dr. Dehua Pei Dissertation: Characterization of s-ribosylhomoeysteinase (LuxS) Employment: Post-Doctoral Fellow, University of Wisconsin