Dept of Molecular Genetics
984 Biological Sciences Bldg
484 W 12th Avenue
Columbus OH 43210
Tel:  614/292-8084
Fax: 614/292-4466

The Ohio State University College of Biological Sciences

Webmaster

Stephen Osmani

Recent Publications

1. Gocke, C.D., Osmani, S.A. and Miller, B.A. (2000) The human homologue of the Aspergillus nuclear migration gene nudC is preferentially expressed in dividing cells and ciliated epithelia.Histochemistry and Cell Biology In Press.
2. De Souza, C.P.C., Wu, L., Spotts, J., Osmani, A. H., and Osmani, S. A. (2000) Mitotic histone H3 phosphorylation by the NIMA kinase in Aspergillus nidulans. Cell. 102 293-302
3. Ye, X. S.,  McGuire, S. L., Wolkow, T., Tang, A., Fincher, R., Hamer, J. E. and Osmani, S. A. (1999) Interaction between developmental and cell cycle regulators is required for morphogenesis in Aspergillus nidulans. EMBO J. 18 6994-7001
4. DeSouza, C.P.C., Ye, X.S. and Osmani, S.A. (1999) Checkpoint defects leading to premature mitosis cause endoreplication of DNA in Aspergillus nidulans. Mol. Biol. Cell.10 3661-3674
5. Osmani, A.H., May, G.S. and Osmani S.A. (1999) The extremely conserved pyroA gene of Aspergillus nidulans is required for pyridoxine synthesis and indirectly for resistance to photosensitizers. J. Biol. Chem.274 23565-23569
6. Bussink, H. J. and Osmani, S. A. (1999)  A MAP kinase (MPKA) is involved in polarized growth in the filamentous fungus Aspergillus nidulans. FEMS Micro. 173 117-125.
7. Miller, B. A., Zhang, M.Y., Gocke, C. D., Osmani, A. H., Bell, L., and Osmani, S. A. (1999) A homolog of the fungal nuclear migration gene nudC is involved in normal and malignant human hematopoiesis. Exp. Hematology17 742-750
8. Ye, X. S., Fincher, A. T., Tang, A., Osmani, A. H. and Osmani, S. A. (1998) Regulation of the APC/C by bimA^APC3 and proteolysis of NIMA. Mol. Biol. Cell.11 3019-3030.
9. Wu, L., Osmani, S. A., and Mirabito, P. M. (1998) A role for NIMA in the nuclear localization of the B-type cyclin, NIME, in Aspergillus nidulans. J. Cell Biol.141 1575-1587.
10. Bussink, H. J. and Osmani, S. A. (1998) A CDK family member (phoA^PHO85) is required to link developmental decisions to environmental conditions in Aspergillus nidulans. EMBO J.173990-4003.
11. Ye, X. S., Xu, G., Fincher, R. R., and Osmani, S. A. (1997) Characterization of the NIMA protein kinase in A. nidulans.  In, Methods in Enzymology. Edited by William G. Dunphy. Academic Press. 283 520-532.
12. Xiang S. Ye, Fincher, R. R., McNeal, K.K., Gygax, S. E., Wexler, A. N., Ryan, K. B., James, S.W.  and Osmani, S.A.  (1997)  Proteolysis and tyrosine phosphorylation of MPF: the role of MCM2 and the initiation of DNA replication to allow tyrosine phosphorylation of cdc2. J. Biol. Chem.272 33384-33393.
13. Ye, X. S. and Osmani S. A. (1997) Regulation of p34^cdc2/cyclin B and NIMA kinases during the G2/M transition and checkpoint responses in Aspergillus nidulans. In, Progress in Cell Cycle Research. Edited by Laurent Meijer, Silvana Guidet and H.Y. Lim Tung. Plenum Press. 3 221-232.
14. Renzi, L., Gersch, M.S., Cambell, M. S., Osmani, S. A., Wu, L., and Gorbsky, G. J. (1997) MPM-2 antibody-reactive phosphorylations can be created in detergent-extracted cells by kinetochore-bound and soluble kinases. J. Cell Sci. 110 2013-2025.
15. Osmani, S. A. and Ye, X. S. (1997) Targets of checkpoints controlling mitosis. Trends in Cell Biology. 7 283-288
16. Martin, M., Osmani, S. A., and Oakley, B. R. (1997) The role of l-tubulin in mitosis and cell cycle progression in Aspergillus nidulans. J. Cell Sci.110 623-633.
17. Ye, X. S., Fincher, A. T., Tang, A., and Osmani, S. A. (1997) The G2/M DNA damage checkpoint inhibits mitosis through Tyr15 phosphorylation of p34^cdc2 in Aspergillus nidulans. EMBO J.16 182-192.