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Biochemistry Faculty

John G. Cogan


Instructor

Phone:  614-292-4470
Fax:      614-292-6773.
email:  cogan.1@osu.edu
Webpage: None


Education:

B.S., 1988:       Mathematical Sciences (minor: Molecular Genetics), The Ohio State University
Ph.D., 1995:    Biochemistry (OSBP), The Ohio State University (advisor: Dr. Arthur Strauch)
Postdoctoral Fellow:    1995-1997, The Ohio State University College of Medicine
Research Scientist:     1997-2004, The Ohio State University College of Medicine

Professional Experience:

1997-1998:        Adjunct Professor, Columbus State Community College, Columbus, OH
2003-present:    Instructor, Introductory Biology Program, The Ohio State University
2004-present:    Course Coordinator, Introductory Biology Program, The Ohio State University
2007-present:    Instructor, Department of Biochemistry, The Ohio State University



Selected publications:

Zhang A, Liu X, Cogan, J.G., Fuerst MD, Polikandriotis JA, Kelm RJ Jr, Strauch AR (2005) "TYB-1 coordinates vascular smooth muscle alpha-actin gene activation by transforming growth factor beta1 and thrombin during differentiation of human pulmonary myofibroblasts" Mol Biol Cell. 16(10), 4931-40.

Cogan, J.G., Subramanian SV, Polikandriotis JA, Kelm RJ Jr, Strauch AR. (2002) "Vascular smooth muscle alpha-actin gene transcription during myofibroblast differentiation requires Sp1/3 protein binding proximal to the MCAT enhancer.", J Biol Chem. 277(39), 36433-42.

Kelm RJ Jr, Cogan, J.G., Elder PK, Strauch AR, Getz MJ. (1999) "Molecular interactions between single-stranded DNA-binding proteins associated with an essential MCAT element in the mouse smooth muscle alpha-actin promoter." ANQ, 19(3), 30-32. Correction, J Biol Chem. 274(20), 14238-45.

Strauch AR, Cogan, J.G., Subramanian SV, Armstrong AT, Sun S, Kelm RJ Jr, Getz MJ. (1997) "Transcriptional activity of the vascular alpha-actin gene as an indicator of cellular injury following cardiac transplant." Transpl Immunol. 5(4), 261-6. Review.

Cogan, J.G., Sun S, Stoflet ES, Schmidt LJ, Getz MJ, Strauch AR. (1995) "Plasticity of vascular smooth muscle alpha-actin gene transcription. Characterization of multiple, single-, and double-strand specific DNA-binding proteins in myoblasts and fibroblasts." J Biol Chem. 270(19) 11310-21.

Sun S, Stoflet ES, Cogan, J.G., Strauch AR, Getz MJ. (1995) "Negative regulation of the vascular smooth muscle alpha-actin gene in fibroblasts and myoblasts: disruption of enhancer function by sequence-specific single-stranded-DNA-binding proteins." Mol Cell Biol. 15(5), 2429-36.

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The Ohio State University - Department of Biochemistry
776 Biological Sciences Building, 484 West 12th Avenue
Columbus, Ohio 43210
TEL: 614.292.6771
FAX: 614.292.6773
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