
The Grass Regulatory Information Server (GRASSIUS, www.grassius.org) provides a resource similar to AGRIS (http://arabidopsis.med.ohio-state.edu/), integrating information on transcription factors (TFs), promoter and cis-regulatory element (CREs) across the grasses grasses (sugarcane, maize, rice, and sorghum), providing a valuable tool for comparative regulatory genomics. GRASSIUS houses three databases, GRASSTFDB (Grass Transcription Factor Database), GRASSPROMDB (Grass Promoter Database) and GRASSREGNET (Grass Regulatory Network Database). GRASSPROMDB has promoter sequences in which predicted and experimentally verified cis-regulatory elements (CREs) are indicated. GRASSTFDB is a collection of TFs from maize, sugarcane, and rice. GRASSREGNET will integrate information housed in GRASSPROMDB and GRASSTFDB in the light of experimentally verified interactions in order to establish regulatory motifs across.